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Title: Deslorelin warning
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ferretmom
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Rank:Carpet Shark

Score: 984
Posts: 700
From: USA
Registered: 11/10/2008
Time spent: 4 hours

(Date Posted:11/01/2009 11:41 AM)

I just found this on the FML.

Date:    Sat, 31 Oct 2009 09:49:40 -0700
From:    Kevin Farlee <
kevin@FARLEE.COM>
Subject: Make sure you get the right deslorelin implant!

My vet is working directly with Dr. Nico Shoemaker in the Netherlands.
He's the primary researcher who's been studying deslorelin for several
years and documenting its effects on ferrets.

I was talking to my vet today about the implants, and she had just
gotten off the phone with the manufacturer, who said there IS NO MORE
until December 7th. That's when their next batch is going to be done.
They were TOTALLY unprepared for the volume of requests coming from
ferret people.

In the conversation, we discussed the buzz on the internet, and she
made a comment that needs to be heard: According to the company that
manufactures the implants, they have not manufactured, much less
exported to the US, enough of the Suprelorin 4.7mg implants to account
for all of the stories going around.

There is another form of Deslorelin implant which is designed for
horses, and is a 2.1mg dose. It goes by the brand name Ovuplant. Dr.
Shoemaker, explored this implant and found that since it is a different
compounding, and a different dosage, not only is it not effective for
ferrets, but it seems to have a detrimental effect. Unfortunately, it
is also widely available in the US, making it easy for a vet to obtain
it and give it as a "Deslorelin implant", which it technically is. Just
not the one that will help ferrets.

My concern is two-fold:
1) I'm concerned that vets will knowingly or through not understanding
the difference, give the wrong implant to ferrets, and have them not
improve.
2) I'm really afraid that in about a year or two, based on #1 above,
you'll see a wave of "That Deslorelin crap is just expensive nonsense.
It doesn't work" sweep the ferret community, and cause a medicine which
could greatly improve the lives of ferrets to be ignored.

If you're getting deslorelin implants for your ferrets, ask your vet
what the brand name is. Ovuplant is the horse one which does not work
well for ferrets. It's a 2.1mg dose. Suprelorin is the one which does
work for ferrets. It's a 4.7mg dose.

Kevin Farlee



Dar24
1# 



Rank:Dook Master

Score:1425
Posts:897
From: Canada
Registered:11/07/2008
Time spent: 8798 hours

RE:Deslorelin warning
(Date Posted:11/02/2009 06:35 AM)

This is a very interesting article.. I copied it to my Ferret Health File for future reference when I talk to my vet..

Thanx for posting it Carol,,


--------------------------------------------------------------

Dar24
2# 



Rank:Dook Master

Score:1425
Posts:897
From: Canada
Registered:11/07/2008
Time spent: 8798 hours

RE:Deslorelin warning
(Date Posted:11/03/2009 06:12 AM)

More on Deslorelin from FML:


Date: Mon, 2 Nov 2009 05:34:53 -0500
From: Sukie Crandall <sukie@MAC.COM>
Subject: Virbac distributes (in Europe) but does not make Suprelorin

The European branch of Virbac distributes it in an agreement with
Peptech. Peptech makes it. It may be that Virbac simply ordered enough
earlier, but Peptech did not expect the number of U.S. orders coming
in.

That may be a way to market it here in the U.S. since Virbac has been
here for something like 2 decades (located in Fort Worth).

See:
<
http://www.virbac.es/p-virbacespubes/pdf/suprelorin/estudios_clinicos/Suprelorinannouncement2008.pdf>

<
http://www.peptech.com/HTML/News_Media/nm_press_release_12sep07.html>

As has been said, be very careful to NOT get the wrong product. The
NON-implant horse version won't last long in the body so it will worsen
things for the same reason that using 24 hour Lupron instead of a
Lupron DEPOTdoes. See:
http://www.miamiferret.org/24hr_lupron.htm

Lupron and Suprelorlin (deslorelin IMPLANT) are in the same family of
drugs.

Sukie (not a vet)

Recommended ferret health links:
http://pets.groups.yahoo.com/group/ferrethealth/
http://ferrethealth.org/archive/
http://www.afip.org/ferrets/index.html
http://www.miamiferret.org/
http://www.ferrethealth.msu.edu/
http://www.ferretcongress.org/
http://www.trifl.org/index.shtml
http://homepage.mac.com/sukie/sukiesferretlinks.html
all ferret topics:
http://listserv.ferretmailinglist.org/archives/ferret-search.html
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